Quantify voxel overlap

Calculate dice coefficient

Voxalign also has a built-in function to verify the accuracy of longitudinal voxel placement. This tool takes as input session 1 and session 2 T1 and spectroscopy DICOMs or NIFTIs, coregisters the two T1s and applies the same transform to the session 1 spectroscopy voxel, and then calculates the dice coefficient between the two spectroscopy voxels. A dice coefficient of 1 reflects perfect overlap.

Voxalign multi-session voxel placement results. Light blue is the session 1 voxel and the dark blue outline is the session 2 voxel outline.

1. Launch the dice coefficient GUI with dice-coef

2. Click "Select output folder" and choose a folder. If you previously ran dice-coef for this same participant, you can choose the same output folder and the skull-stripped T1s and linear coregistration will be re-used.

3. Provide all other files.

4. Click "Calculate dice coefficient"

5. The dice coefficient will be printed to the terminal, and a fsleyes window will be opened, with the coregistered T1s and MRS voxels overlaid.